Nutlin-3
Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.
Product Specifications
CAS Number
548472-68-0
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
COC1=CC (OC (C) C) =C (C=C1) C1=NC (C (N1C (=O) N1CCNC (=O) C1) C1=CC=C (Cl) C=C1) C1=CC=C (Cl) C=C1
Molecular Formula
C30H30Cl2N4O4
Molecular Weight
581.49
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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