PRIMA-1
A specific mutant p53 reactivator that induces apoptosis and enhances chemotherapeutic cytotoxicity in cancer cell lines; is efficacious against myeloma cells with differential p53 genotypes, causes the demethylation of TP73, through DNMT1 depletion, to subsequently enhance UPR; selectively induces apoptosis and cell cycle arrest in p53 mutant cells compared to CAPAN-2 cells.Blood Cancer Phase 2 Clinical.
Product Specifications
CAS Number
5608-24-2
Product Name Alternative
PRIMA 1 | PRIMA1
Field of Research
Neuroscience
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 44 mg/mL
Smiles
O=C1C (CO) (CO) N2CCC1CC2
Molecular Formula
C9H15NO3
Molecular Weight
185.2203
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Azabicyclo[2.2.2]octan-3-one, 2,2-bis (hydroxymethyl) -
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
