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Elesclomol

Elesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells; selectively kills cisplatin-resistant tumor cells through increased ROS, markedly enhances the therapeutic index of paclitaxel against human tumor xenograft models. Ovarian Cancer Phase 2 Clinical.

Product Specifications

CAS Number

488832-69-5

Product Name Alternative

STA-4783 | STA4783 | STA 4783

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 22 mg/mL

Smiles

O=C (NN (C) C (C1=CC=CC=C1) =S) CC (NN (C) C (C2=CC=CC=C2) =S) =O

Molecular Formula

C19H20N4O2S2

Molecular Weight

400.5177

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Propanedioic acid, 1,3-bis[2-methyl-2- (phenylthioxomethyl) hydrazide]

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