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Ampicillin sodium

Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia. (In Vitro) :Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL. (In Vivo) :Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia.

Product Specifications

CAS Number

69-52-3

Product Name Alternative

Alpen-N, Amcill-S, Ampicillin natrium, Ampicillin sodium

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO:37 mg/mL (99.62 mM) ; Ethanol:74 mg/mL (199.25 mM) ; Water:74 mg/mL (199.25 mM)

Smiles

N (C (=O) [C@@H] (c1ccccc1) N) [C@H]1[C@@H]2N (C1=O) [C@H] (C (S2) (C) C) C (=O) [O-].[Na+]

Molecular Formula

C16H18N3N/AO4S

Molecular Weight

371.39

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-Thia-1-azabicyclo (3.2.0) heptane-2-carboxylic acid, 6- ((aminophenylacetyl) amino) -3,3-dimethyl-7-oxo-, monosodium salt, (2S- (2alpha,5alpha,6beta (S*) ) ) -
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