KRas-IN-1
A chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM; binds to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.
Product Specifications
CAS Number
84783-01-7
Product Name Alternative
MDK-3017 | MDK3017 | MDK 3017 | K-Ras-IN-2 | K-Ras Inhibitor-2
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 28 mg/mL
Smiles
S=C (C1=CC=CC=C1O) N2CCCC2
Molecular Formula
C11H13NOS
Molecular Weight
207.292
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Methanethione, (2-hydroxyphenyl) -1-pyrrolidinyl-
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