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KRas-IN-1

A chemical fragment hit that binds to K-Ras (G12D) with affinities of 1.3-2 mM; binds to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.

Product Specifications

CAS Number

84783-01-7

Product Name Alternative

MDK-3017 | MDK3017 | MDK 3017 | K-Ras-IN-2 | K-Ras Inhibitor-2

Field of Research

Signal Transduction

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 28 mg/mL

Smiles

S=C (C1=CC=CC=C1O) N2CCCC2

Molecular Formula

C11H13NOS

Molecular Weight

207.292

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Methanethione, (2-hydroxyphenyl) -1-pyrrolidinyl-

Available Sizes

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