What is the catalog number for SD-208?

The catalog number for SD-208 is orb1224418.

What sizes are available for SD-208?

SD-208 is available in the following size(s): 200 mg, 500 mg, 1 g, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does SD-208 come in?

SD-208 is available in 9 different pack sizes.

SD-208 is currently made to order / not held in immediate stock. Contact us for lead time.

SD-208

SD-208 is a potent, selective TGF-β receptor I kinase (TGF-βRI) inhibitor with IC50 of 48 nM, >100-fold selectivity over TGF-βRII kinase and >20-fold over a panel of related protein kinases; inhibits the growth inhibition of TGF-beta-sensitive CCL64 cells mediated by recombinant TGF-β1 or TGF-β2 or of TGF-β-containing glioma cell supernatant with EC50 of 0.1 uM; inhibits constitutive and TGF-β–induced invasion of glioma cells, inhibits TGF-β signaling in immune effector cells; blocks TGF-β signaling in the brain and inhibits the growth of syngeneic SMA-560 experimental gliomas in vivo.