2-NP
2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast Y and fibrosarcoma cells.
Product Specifications
CAS Number
65182-56-1
Purity
>98% (HPLC)
Solubility
DMSO: > 10 mM
Smiles
C1=C/C (=C/2\C=CC3=C (N2) N=CC=C3) /C (=O) C=C1
Molecular Formula
C14H10N2O
Molecular Weight
222.24
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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