AIM-100
AIM-100 (AIM100) is a highly potent inhibitor of Ack1 (TNK2) (IC50=24 nM), selective for Ack1 over ABL1, BTK, Lck and LYN; inhibits Ack1 Tyr284-phosphorylation attenuated pTyr267-AR transcriptional activity which in turn resulted in cell cycle arrest; inhibits pTyr284 -Ack1 expression, and prostate cancer cell proliferation.
Product Specifications
CAS Number
873305-35-2
Product Name Alternative
AIM 100 | AIM100
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C12=NC=NC (NC[C@H]3OCCC3) =C1C (C4=CC=CC=C4) =C (C5=CC=CC=C5) O2
Molecular Formula
C23H21N3O2
Molecular Weight
371.44
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Furo[2,3-d]pyrimidin-4-amine, 5,6-diphenyl-N-[[ (2S) -tetrahydro-2-furanyl]methyl]-
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
C9095-17D 100 µL
Cytochrome P450 (CYP4A1, CYP4A2, CYP4A3) (Not for Export EU)
Sign In for Pricing
View Details 
