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SPI 112

SPI-112, the SPI-112 methyl ester analog was able to inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.

Product Specifications

CAS Number

1051387-90-6

Product Name Alternative

SPI-112 | SPI112 | SPI 112

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (106.73 mM)

Smiles

O=C (O) c1cccc (N/N=C/2\C (=O) Nc3c2cc (S (=O) (=O) NCc2ccc (F) cc2) cc3) c1

Molecular Formula

C22H17FN4O5S

Molecular Weight

468.45

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(Z) -3- (2- (5- (N- (4-Fluorobenzyl) sulfamoyl) -2-oxoindolin-3-ylidene) hydrazinyl) benzoic acid

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