SPI 112
SPI-112, the SPI-112 methyl ester analog was able to inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2.
Product Specifications
CAS Number
1051387-90-6
Product Name Alternative
SPI-112 | SPI112 | SPI 112
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (106.73 mM)
Smiles
O=C (O) c1cccc (N/N=C/2\C (=O) Nc3c2cc (S (=O) (=O) NCc2ccc (F) cc2) cc3) c1
Molecular Formula
C22H17FN4O5S
Molecular Weight
468.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(Z) -3- (2- (5- (N- (4-Fluorobenzyl) sulfamoyl) -2-oxoindolin-3-ylidene) hydrazinyl) benzoic acid
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