MPEP
MPEP is a potent and selective antagonist of the metabotropic glutamate receptor 5 (mGlu5), demonstrating an IC50 of 36 nM. It shows negligible activity at other mGlu receptor subtypes (mGlu1b/2/3/4a/7b/8a/6) . This compound is widely used in neuroscience research to investigate mGlu5 function in vitro and in animal models of neurological disorders.
Product Specifications
CAS Number
96206-92-7
Product Name Alternative
MPEP, inhibit, mGluR5, Metabotropic glutamate receptors, mGluR, Inhibitor
Field of Research
Neuroscience
Purity
99.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.35 mM) ; Ethanol:37 mg/mL (191.47 mM) ; DMSO:37 mg/mL (191.47 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cl.Cc1cccc (n1) C#Cc1ccccc1
Molecular Formula
C14H11N
Molecular Weight
193.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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