MPEP

MPEP is a potent and selective antagonist of the metabotropic glutamate receptor 5 (mGlu5), demonstrating an IC50 of 36 nM. It shows negligible activity at other mGlu receptor subtypes (mGlu1b/2/3/4a/7b/8a/6) . This compound is widely used in neuroscience research to investigate mGlu5 function in vitro and in animal models of neurological disorders.

Product Specifications

CAS Number

96206-92-7

Product Name Alternative

MPEP, inhibit, mGluR5, Metabotropic glutamate receptors, mGluR, Inhibitor

Field of Research

Neuroscience

Purity

99.31% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.35 mM) ; Ethanol:37 mg/mL (191.47 mM) ; DMSO:37 mg/mL (191.47 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)