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2-Iminobiotin hydrobromide

2-Iminobiotin hydrobromide is a cyclic guanidino derivative of biotin which functions as a reversible, competitive inhibitor of both inducible (iNOS) and neuronal (nNOS) nitric oxide synthase isoforms. This small molecule is utilized in vitro and in vivo to investigate the pathophysiological roles of NO overproduction in models of inflammation, sepsis, and neurological disorders.

Product Specifications

CAS Number

76985-52-9

Product Name Alternative

2 Iminobiotin hydrobromide, 2-Iminobiotin, 2Iminobiotin hydrobromide, 2-Iminobiotin Hydrobromide, Guanidinobiotin, Inhibitor, iNOS, NOS, NOSynthase, inhibit, nNOS, NO Synthase, Nitric oxide synthases

Field of Research

Immunology & Inflammation

Purity

98.13% (May vary between batches)

Solubility

DMSO:12.5 mg/mL (38.55 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.17 mM)

Smiles

[H][C@] (CS[C@H]1CCCCC (O) =O) ([C@]1 ([H]) N2) NC2=N.Br

Molecular Formula

C10H18BrN3O2S

Molecular Weight

324.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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