Ulixertinib
Ulixertinib (BVD-523) is a potent and reversible dual inhibitor of ERK1 and ERK2, exhibiting an IC50 below 0.3 nM for ERK2. It is widely used in preclinical cancer research to investigate MAPK pathway signaling in both cellular and animal models of various malignancies.
Product Specifications
CAS Number
869886-67-9
Product Name Alternative
Ulixertinib, VRT 752271, VRT752271, VRT-752271, Inhibitor, Extracellular signal regulated kinases, ERK, ERK2, inhibit, BVD 523, BVD523, BVD-523
Field of Research
Signal Transduction
Purity
99.31% (May vary between batches)
Solubility
Ethanol:12 mg/mL (27.69 mM) ; DMSO:250 mg/mL (576.93 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (18.46 mM)
Smiles
CC (C) Nc1cc (-c2c[nH]c (c2) C (=O) N[C@H] (CO) c2cccc (Cl) c2) c (Cl) cn1
Molecular Formula
C21H22Cl2N4O2
Molecular Weight
433.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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