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14-Deoxyandrographolide

14-Deoxyandrographolide, a hepatoprotective diterpenoid from Andrographis paniculata, inhibits TNF-α-induced hepatocyte apoptosis by promoting TNFRSF1A release. This mechanism supports its application in researching liver injury models, both in vitro and in vivo, for studying inflammatory apoptosis pathways.

Product Specifications

CAS Number

4176-97-0

Product Name Alternative

14Deoxyandrographolide, 14-Deoxyandrographolide, 14 Deoxyandrographolide, Apoptosis, Ca channels, Calcium Channel, Ca2+ channels, bovine neutrophils, inhibit, Inhibitor, rat, platelet activating factor, uterine smooth muscle

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Purity

99.89% (May vary between batches)

Solubility

DMSO:3.35 mg/mL (10.02 mM)

Smiles

[H][C@]12CCC (=C) [C@@H] (CCC3=CCOC3=O) [C@]1 (C) CC[C@@H] (O) [C@@]2 (C) CO

Molecular Formula

C20H30O4

Molecular Weight

334.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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