14-Deoxyandrographolide
14-Deoxyandrographolide, a hepatoprotective diterpenoid from Andrographis paniculata, inhibits TNF-α-induced hepatocyte apoptosis by promoting TNFRSF1A release. This mechanism supports its application in researching liver injury models, both in vitro and in vivo, for studying inflammatory apoptosis pathways.
Product Specifications
CAS Number
4176-97-0
Product Name Alternative
14Deoxyandrographolide, 14-Deoxyandrographolide, 14 Deoxyandrographolide, Apoptosis, Ca channels, Calcium Channel, Ca2+ channels, bovine neutrophils, inhibit, Inhibitor, rat, platelet activating factor, uterine smooth muscle
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.89% (May vary between batches)
Solubility
DMSO:3.35 mg/mL (10.02 mM)
Smiles
[H][C@]12CCC (=C) [C@@H] (CCC3=CCOC3=O) [C@]1 (C) CC[C@@H] (O) [C@@]2 (C) CO
Molecular Formula
C20H30O4
Molecular Weight
334.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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