SORT-PGRN interaction inhibitor 1
This small molecule inhibitor potently disrupts the sortilin-progranulin interaction with an IC50 of 2 μM. It is a valuable research tool for studying progranulin-related pathways in neurodegenerative diseases, such as frontotemporal dementia, in both cellular and animal models.
Product Specifications
CAS Number
100957-85-5
Product Name Alternative
Progranulin, SORT PGRN interaction inhibitor 1, sortilin, sortilin-progranulin, SORTPGRN interaction inhibitor 1, SORT-PGRN interaction inhibitor 1, PPI, PGRN, Inhibitor, inhibit, Neurotensin Receptor, NeurotensinReceptor
Field of Research
Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Purity
98.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.74 mM) ; DMSO:60 mg/mL (232.27 mM)
Smiles
CC (C) (C) C1=NN (CC2=CC=CC=C2) C (=C1) C (O) =O
Molecular Formula
C15H18N2O2
Molecular Weight
258.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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