A-484954
A-484954 is a potent and selective inhibitor of eukaryotic elongation factor-2 (eEF2) with an IC50 of 280 nM. This compound is a valuable research tool for studying protein synthesis mechanisms and has been utilized in both in vitro and in vivo models to investigate cellular processes such as apoptosis and autophagy.
Product Specifications
CAS Number
142557-61-7
Product Name Alternative
A 484954, A484954, A-484954, Calmodulin-dependent kinases, Calmodulin-dependent protein kinases, CaMK, Autophagy, eEF2, Inhibitor, inhibit
Field of Research
Cell Biology, Infectious Disease & Virology, Neuroscience
Purity
97.47% (May vary between batches)
Solubility
DMSO:24.5 mg/mL (84.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.91 mM) ; H2O:Insoluble
Smiles
CCn1c (=O) n (C2CC2) c2nc (N) c (cc2c1=O) C (N) =O
Molecular Formula
C13H15N5O3
Molecular Weight
289.29
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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