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A-484954

A-484954 is a potent and selective inhibitor of eukaryotic elongation factor-2 (eEF2) with an IC50 of 280 nM. This compound is a valuable research tool for studying protein synthesis mechanisms and has been utilized in both in vitro and in vivo models to investigate cellular processes such as apoptosis and autophagy.

Product Specifications

CAS Number

142557-61-7

Product Name Alternative

A 484954, A484954, A-484954, Calmodulin-dependent kinases, Calmodulin-dependent protein kinases, CaMK, Autophagy, eEF2, Inhibitor, inhibit

Field of Research

Cell Biology, Infectious Disease & Virology, Neuroscience

Purity

97.47% (May vary between batches)

Solubility

DMSO:24.5 mg/mL (84.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.91 mM) ; H2O:Insoluble

Smiles

CCn1c (=O) n (C2CC2) c2nc (N) c (cc2c1=O) C (N) =O

Molecular Formula

C13H15N5O3

Molecular Weight

289.29

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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