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TC-I2000

TC-I2000 is a potent and selective TRPM8 channel antagonist, inhibiting icilin-induced activation with an IC50 of 53 nM in recombinant systems. This small molecule inhibitor is a valuable research tool for studying TRPM8's role in thermosensation, pain, and cancer in both cellular and animal models.

Product Specifications

CAS Number

1159996-20-9

Product Name Alternative

TC I2000, TC-I 2000, TCI2000, TC-I2000, TC-I-2000, TRP Channel, TRPM8, TRPV Channel, TRPChannel, TRPVChannel

Field of Research

Pharmacology & Drug Discovery

Purity

98.87% (May vary between batches)

Solubility

DMSO:4.15 mg/mL (10.01 mM)

Smiles

C (NC1=CC=C (F) C=C1) (=O) N2C (C=3C (CC2) =CC=CC3) C4=CC=C (C (F) (F) F) C=C4

Molecular Formula

C23H18F4N2O

Molecular Weight

414.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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