TC-I2000
TC-I2000 is a potent and selective TRPM8 channel antagonist, inhibiting icilin-induced activation with an IC50 of 53 nM in recombinant systems. This small molecule inhibitor is a valuable research tool for studying TRPM8's role in thermosensation, pain, and cancer in both cellular and animal models.
Product Specifications
CAS Number
1159996-20-9
Product Name Alternative
TC I2000, TC-I 2000, TCI2000, TC-I2000, TC-I-2000, TRP Channel, TRPM8, TRPV Channel, TRPChannel, TRPVChannel
Field of Research
Pharmacology & Drug Discovery
Purity
98.87% (May vary between batches)
Solubility
DMSO:4.15 mg/mL (10.01 mM)
Smiles
C (NC1=CC=C (F) C=C1) (=O) N2C (C=3C (CC2) =CC=CC3) C4=CC=C (C (F) (F) F) C=C4
Molecular Formula
C23H18F4N2O
Molecular Weight
414.4
Storage Conditions
-20°C
Notes
For research use only.
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