Beta-Carotene
β-Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A. (In Vitro) :β-Carotene up-regulates PPAR-γ expression and ROS production in MCF-7 cancer cells.β-Carotene (1-100 μM; 72 hours) remarkably decreases the survival of MCF-7 cells in a dose-dependent manner.β-Carotene (50 μM; 24-72 hours) significantly enhances the expression levels of PPAR-γ mRNA and protein in a time-dependent manner.β-Carotene down-regulates the COX-2 but up-regulates the p21 mRNA level and protein expression in a time dependent manner.β-Carotene significantly increases the percentage of early apoptosis and the effect was partly attenuated by pre-incubation with GW9662 (HY-16578) or GSH (HY-D0187) .β-Carotene induces cytochrome C release.
Product Specifications
CAS Number
7235-40-7
Product Name Alternative
Food Orange 5 | KPMK | Lucarotin | NSC 62794 | Provatene | Provitamin A | Solatene
Purity
>98% (HPLC)
Solubility
Ethanol: 5 mg/mL warmed (9.31 mM) ; DMSO: 4 mg/mL warmed (7.45 mM)
Smiles
CC (/C=C/C1=C (C) CCCC1 (C) C) =C\C=C\C (C) =C\C=C\C=C (C) \C=C\C=C (C) \C=C\C2=C (C) CCCC2 (C) C
Molecular Formula
C40H56
Molecular Weight
536.87
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(all-E) -1,1'- (3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl) bis (2,6,6-trimethylcyclohexene)
Available Sizes
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