SPDP
A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. (In Vitro) :Equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) are activated using SPDP.
Product Specifications
CAS Number
68181-17-9
Product Name Alternative
SPDP Crosslinker, SPDP Cross linker, SPDP Cross-linker, SPDP NHS ester
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (ON1C (CCC1=O) =O) CCSSC2=NC=CC=C2
Molecular Formula
C12H12N2O4S2
Molecular Weight
312.3647
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Propanoic acid, 3- (2-pyridinyldithio) -, 2,5-dioxo-1-pyrrolidinyl ester
Available Sizes
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