SRT 1720
A potent, selective SIRT1 activator with EC1.5 of 0.16 uM; displays good selectivity for activation of SIRT1 versus SIRT2 (EC1.5=37 uM) and SIRT3 (EC1.5>300 uM) ; 1,000-fold more potent than resveratrol; improve insulin sensitivity, lower plasma glucose, and increase mitochondrial capacity in obese mice model.
Product Specifications
CAS Number
925434-55-5
Product Name Alternative
SRT-1720 | SRT1720
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
C1CN (CCN1) CC2=CSC3=NC (=CN23) C4=CC=CC=C4NC (=O) C5=NC6=CC=CC=C6N=C5
Molecular Formula
C25H23N7OS
Molecular Weight
469.5614
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Quinoxalinecarboxamide, N-[2-[3- (1-piperazinylmethyl) imidazo[2,1-b]thiazol-6-yl]phenyl]-
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