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SRT 1720

A potent, selective SIRT1 activator with EC1.5 of 0.16 uM; displays good selectivity for activation of SIRT1 versus SIRT2 (EC1.5=37 uM) and SIRT3 (EC1.5>300 uM) ; 1,000-fold more potent than resveratrol; improve insulin sensitivity, lower plasma glucose, and increase mitochondrial capacity in obese mice model.

Product Specifications

CAS Number

925434-55-5

Product Name Alternative

SRT-1720 | SRT1720

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

C1CN (CCN1) CC2=CSC3=NC (=CN23) C4=CC=CC=C4NC (=O) C5=NC6=CC=CC=C6N=C5

Molecular Formula

C25H23N7OS

Molecular Weight

469.5614

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Quinoxalinecarboxamide, N-[2-[3- (1-piperazinylmethyl) imidazo[2,1-b]thiazol-6-yl]phenyl]-

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