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Alflutinib methanesulfonate

Alflutinib methanesulfonate (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.Lung Cancer Phase 1 Clinical (In Vitro) :Alflutinib (Furmonertinib) mesylate is designed to inhibit EGFR active mutations as well as the T790M acquired resistant mutation.

Product Specifications

CAS Number

2130958-55-1

Product Name Alternative

AST2818 | AST-2818 | ASK120067

Purity

>98% (HPLC)

Solubility

DMSO : 5 mg/mL 7.52 mM

Smiles

CN (C) CCN (C) c1nc (OCC (F) (F) F) c (Nc2nccc (n2) c3cn (C) c4ccccc34) cc1NC (=O) C=C.CS (=O) (=O) O

Molecular Formula

C29H35F3N8O5S

Molecular Weight

664.705

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (2- ((2- (dimethylamino) ethyl) (methyl) amino) -5- ((4- (1-methyl-1H-indol-3-yl) pyrimidin-2-yl) amino) -6- (2,2,2-trifluoroethoxy) pyridin-3-yl) acrylamide methanesulfonate

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