Bicyclol
Bicyclol, also known as SY 801, is a hepatoprotective agent. Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways. Bicyclol attenuates tetracycline-induced fatty liver associated with inhibition of hepatic ER stress and apoptosis in mice. Bicyclol promotes toll-like 2 receptor recruiting inosine 5'-monophosphate dehydrogenase II to exert its anti-inflammatory effect.
Product Specifications
CAS Number
118159-48-1
Product Name Alternative
Bicyclol | SY 801 | SY-801 | SY801
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 68 mg/mL. 174.21 mM
Smiles
COc1c2c (c (c (c1) CO) c1c3c (c (cc1C (=O) OC) OC) OCO3) OCO2
Molecular Formula
C19H18O9
Molecular Weight
390.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5'- (hydroxymethyl) -7,7'-dimethoxy-[4,4'-bi-1,3-benzodioxole]-5-carboxylic acid, methyl ester
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
4mL polyethylene transfer pipets, bulb draw 3.5 mL, length 15 cm. 28 drops per mL, 500/cs
CDH11 (Cadherin 11, Type 2, OB-Cadherin (Osteoblast), CAD11, CDHOB, OB, OSF-4) (FITC)
CDH11 (Cadherin 11, Type 2, OB-Cadherin (Osteoblast), CAD11, CDHOB, OB, OSF-4) (FITC)