CNX-774
CNX-774 is a potent Btk inhibitor (IC50 < 1 nM) . Recently Bruton's tyrosine kinase (BTK), a crucial terminal kinase enzyme in the B-cell antigen receptor (BCR) signaling pathway, has emerged as an attractive target for therapeutic intervention in human malignancies and autoimmune disorders.
Product Specifications
CAS Number
1202759-32-7
Product Name Alternative
CNX774 | CNX 774 | CNX-774
Field of Research
Cell Biology
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 45 mg/mL. 90.09 mM
Smiles
C1c (ccc (c1) Oc1ccnc (c1) C (=O) NC) Nc1nc (c (cn1) F) Nc1cccc (c1) NC (=O) C=C
Molecular Formula
C26H22FN7O3
Molecular Weight
499.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (4- ((4- ((3-acrylamidophenyl) amino) -5-fluoropyrimidin-2-yl) amino) phenoxy) -N-methylpicolinamide
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