Skepinone-L
Skepinone-L is an ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50s = 5 nM) and p38β (97% inhibition at 1 μM) .
Product Specifications
CAS Number
1221485-83-1
Product Name Alternative
Skepinone-L
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL 117.53 mM; H2O : < 0.1 mg/mL
Smiles
C12c (C (=O) c3c (CC1) ccc (c3) OC[C@@H] (CO) O) ccc (c2) Nc1c (cc (cc1) F) F
Molecular Formula
C24H21F2NO4
Molecular Weight
425.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-[ (2,4-difluorophenyl) amino]-7-[ (2R) -2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5-one
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