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Skepinone-L

Skepinone-L is an ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50s = 5 nM) and p38β (97% inhibition at 1 μM) .

Product Specifications

CAS Number

1221485-83-1

Product Name Alternative

Skepinone-L

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 50 mg/mL 117.53 mM; H2O : < 0.1 mg/mL

Smiles

C12c (C (=O) c3c (CC1) ccc (c3) OC[C@@H] (CO) O) ccc (c2) Nc1c (cc (cc1) F) F

Molecular Formula

C24H21F2NO4

Molecular Weight

425.42

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-[ (2,4-difluorophenyl) amino]-7-[ (2R) -2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a, d]cyclohepten-5-one

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