C-Kit-IN-1

DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM) . (In Vitro) :c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.