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C-Kit-IN-1

DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM) . (In Vitro) :c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.

Product Specifications

CAS Number

1225278-16-9

Field of Research

Signal Transduction

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL. 204.30 mM

Smiles

Cn1cc (cn1) c1nccc (c1) Oc1c (cc (c (c1) F) NC (=O) C1 (CC1) C (=O) Nc1ccccc1) F

Molecular Formula

C26H21F2N5O3

Molecular Weight

489.47

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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