SCH 23390 hydrochloride
SCH-23390 hydrochloride is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively) . SCH-23390 hydrochloride is also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively) . It blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors.
Product Specifications
CAS Number
125941-87-9
Product Name Alternative
SCH-23390 | SCH23390 | SCH 23390 hydrochloride
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 32 mg/mL. 98.69 mM; H2O : < 0.1 mg/mL
Smiles
OC1=C (Cl) C=C2CCN (C) C[C@H] (C3=CC=CC=C3) C2=C1.[H]Cl
Molecular Formula
C17H19Cl2NO
Molecular Weight
324.24
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(R) -8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
Available Sizes
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