UNC0631
UNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53.
Product Specifications
CAS Number
1320288-19-4
Product Name Alternative
UNC0631, UNC 0631, UNC-0631
Purity
>98% (HPLC)
Solubility
DMSO : 16.67 mg/mL. 26.21 mM; H2O : < 0.1 mg/mL
Smiles
COc1c (OCCCN2CCCCC2) cc2nc (nc (NC3CCN (CC4CCCCC4) CC3) c2c1) N1CCCN (CC1) C (C) C
Molecular Formula
C37H61N7O2
Molecular Weight
635.93
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (1- (cyclohexylmethyl) piperidin-4-yl) -2- (4-isopropyl-1,4-diazepan-1-yl) -6-methoxy-7- (3- (piperidin-1-yl) propoxy) quinazolin-4-amine
Available Sizes
Frequently Asked Questions
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