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E6446 dihydrochloride

E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.

Product Specifications

CAS Number

1345675-25-3

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 7.6 mg/mL (14.55 mM)

Smiles

C1 (c2ccc (OCCCN3CCCC3) cc2) nc2ccc (OCCCN3CCCC3) cc2o1.Cl.Cl

Molecular Formula

C27H37Cl2N3O3

Molecular Weight

522.51

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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