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TUG-891

TUG-891 is a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which demonstrates both potential opportunity and possible challenges to therapeutic agonism. Activation of human FFA4 by TUG-891 also resulted in rapid phosphorylation and internalization of the receptor. TUG-891 was also a potent agonist of mouse FFA4, but it showed only limited selectivity over mouse FFA1, complicating its use in vivo in this species.

Product Specifications

CAS Number

1374516-07-0

Product Name Alternative

TUG-891 | TUG 891 | TUG891

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 180 mg/mL 493.95 mM

Smiles

C1 (c (ccc (c1) F) c1ccc (cc1) C) COc1ccc (cc1) CCC (=O) O

Molecular Formula

C23H21FO3

Molecular Weight

364.41

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

3- (4- ((4-fluoro-4'-methyl-[1,1'-biphenyl]-2-yl) methoxy) phenyl) propanoic acid

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