TUG-891
TUG-891 is a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), which demonstrates both potential opportunity and possible challenges to therapeutic agonism. Activation of human FFA4 by TUG-891 also resulted in rapid phosphorylation and internalization of the receptor. TUG-891 was also a potent agonist of mouse FFA4, but it showed only limited selectivity over mouse FFA1, complicating its use in vivo in this species.
Product Specifications
CAS Number
1374516-07-0
Product Name Alternative
TUG-891 | TUG 891 | TUG891
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 180 mg/mL 493.95 mM
Smiles
C1 (c (ccc (c1) F) c1ccc (cc1) C) COc1ccc (cc1) CCC (=O) O
Molecular Formula
C23H21FO3
Molecular Weight
364.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3- (4- ((4-fluoro-4'-methyl-[1,1'-biphenyl]-2-yl) methoxy) phenyl) propanoic acid
Available Sizes
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