KML29
KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM) . It has not inhibitory for FAAH (IC50 > 50 μM) . It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA) .
Product Specifications
CAS Number
1380424-42-9
Product Name Alternative
KML-29 | KML29 | KML 29
Purity
>98% (HPLC)
Solubility
DMSO : 50 mg/mL. 91.01 mM; H2O : < 0.1 mg/mL
Smiles
O=C (OC (C (F) (F) F) C (F) (F) F) N1CCC (C (c2ccc3OCOc3c2) (O) c2cc3OCOc3cc2) CC1
Molecular Formula
C24H21F6NO7
Molecular Weight
549.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,1,1,3,3,3-hexafluoropropan-2-yl 4- (bis (benzo[d][1,3]dioxol-5-yl) (hydroxy) methyl) piperidine-1-carboxylate
Available Sizes
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