G007-LK
G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007-LK was first discovered by Dr. Stefan Krauss's team.
Product Specifications
CAS Number
1380672-07-0
Product Name Alternative
G007LK | G007LK | G007 LK
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 30 mg/mL. 56.61 mM
Smiles
CS (=O) (=O) c1cnc (cc1) c1nnc (n1c1ccccc1Cl) /C=C/c1nnc (o1) c1ccc (cc1) C#N
Molecular Formula
C25H16ClN7O3S
Molecular Weight
529.96
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -4- (5- (2- (4- (2-chlorophenyl) -5- (5- (methylsulfonyl) pyridin-2-yl) -4H-1,2,4-triazol-3-yl) vinyl) -1,3,4-oxadiazol-2-yl) benzonitrile
Available Sizes
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