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IWP-L6

IWP-L6, also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX, is a potent inhibitor of PORCN (EC50 = 0.5 nM) . Porcupine is a member of the membrane-bound O-acyltransferase family of proteins. It catalyzes the palmitoylation of Wnt proteins, a process required for their secretion and activity.

Product Specifications

CAS Number

1427782-89-5

Product Name Alternative

IWP-L6 | PORCN Inhibitor III

Purity

>98% (HPLC)

Solubility

DMSO : 1.43 mg/mL 3.03 mM

Smiles

O=C (CSc1nc2c (SCC2) c (=O) n1c1ccccc1) Nc1ncc (cc1) c1ccccc1

Molecular Formula

C25H20N4O2S2

Molecular Weight

472.58

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (5-phenyl-2-pyridinyl) -2-[ (3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl) thio]-acetamide

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