IWP-L6
IWP-L6, also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX, is a potent inhibitor of PORCN (EC50 = 0.5 nM) . Porcupine is a member of the membrane-bound O-acyltransferase family of proteins. It catalyzes the palmitoylation of Wnt proteins, a process required for their secretion and activity.
Product Specifications
CAS Number
1427782-89-5
Product Name Alternative
IWP-L6 | PORCN Inhibitor III
Purity
>98% (HPLC)
Solubility
DMSO : 1.43 mg/mL 3.03 mM
Smiles
O=C (CSc1nc2c (SCC2) c (=O) n1c1ccccc1) Nc1ncc (cc1) c1ccccc1
Molecular Formula
C25H20N4O2S2
Molecular Weight
472.58
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (5-phenyl-2-pyridinyl) -2-[ (3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl) thio]-acetamide
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