What is the catalog number for CPI-169?

The catalog number for CPI-169 is orb1223296.

What sizes are available for CPI-169?

CPI-169 is available in the following size(s): 200 mg, 500 mg, 1 g, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does CPI-169 come in?

CPI-169 is available in 9 different pack sizes.

CPI-169 is currently made to order / not held in immediate stock. Contact us for lead time.

CPI-169

CPI-169 is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) with an IC50 value of <1nM for polycomb repressive complex 2 (PRC2) . CPI-169 was shown to inhibit tumor growth in a NHL xenograft model, reducing global H3K27me3.1 It has also been shown to synergize with the B-cell lymphoma inhibitor, ABT-199, to suppress the growth of NHL cell lines.

Product Specifications

CAS Number

1450655-76-1

Product Name Alternative

CPI-169 | CPI 169 | CPI169

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 59 mg/mL. 111.60 mM

Smiles

CCS (=O) (=O) N1CCC (CC1) C (C) n1c2ccccc2c (C (=O) NCc2c (OC) cc (C) [nH]c2=O) c1C

Molecular Formula

C27H36N4O5S

Molecular Weight

528.66

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(R, Z) -1- (1- (1- (ethylsulfonyl) piperidin-4-yl) ethyl) -N- ((2-hydroxy-4-methoxy-6-methylpyridin-3-yl) methyl) -2-methyl-1H-indole-3-carbimidic acid