UNC-0642
UNC0642 is a potent, selective inhibitor of G9a/GLP with improved PK properties. UNC0642 exhibits an in vitro IC50 100-fold over 13 other HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. In cells, UNC0642 results in a potent reduction of H3K9me2 in MDA MB231 cells with IC50 = 106 nM.
Product Specifications
CAS Number
1481677-78-4
Product Name Alternative
AHU-377
Purity
>98% (HPLC)
Solubility
DMSO : 295 mg/mL. 539.60 mM
Smiles
CC (N1CCC (Nc2c3cc (OC) c (OCCCN4CCCC4) cc3nc (N3CCC (F) (F) CC3) n2) CC1) C
Molecular Formula
C29H44F2N6O2
Molecular Weight
546.69
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (4,4-Difluoro-1-piperidinyl) -6-methoxy-N-[1- (1-methylethyl) -4-piperidinyl]-7-[3- (1-pyrrolidinyl) propoxy]-4-quinazolinamine
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
217749 100 mg
Ro 20-1724 (4- (3-Butoxy-4-methoxybenzyl) -2-imidazolidinone) discontinued. See R1900-02
Sign In for Pricing
View Details 
MBS1411162-01 0.02 mg (E-Coli)
Recombinant Escherichia coli Putative phosphotransferase ydiA (ydiA)
Sign In for Pricing
View Details MBS1411162-02 0.02 mg (Yeast)
Recombinant Escherichia coli Putative phosphotransferase ydiA (ydiA)
Sign In for Pricing
View Details MBS1411162-03 0.1 mg (E-Coli)
Recombinant Escherichia coli Putative phosphotransferase ydiA (ydiA)
Sign In for Pricing
View Details MBS1411162-04 0.1 mg (Yeast)
Recombinant Escherichia coli Putative phosphotransferase ydiA (ydiA)
Sign In for Pricing
View Details