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Tyrphostin AG 879

AG-879 is a tyrphostin compound that inhibits nerve growth factor-dependent TrkA tyrosine phosphorylation in PC-12 cells, HER2-ErbB2 kinase in several breast and ovarian cancer cell lines, and the VEGF receptor FLK1. It decreases cellular proliferation in human muscular sarcoma cell lines.

Product Specifications

CAS Number

148741-30-4

Product Name Alternative

Val-boroPro (mesylate) | PT100 (mesylate)

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 30 mg/mL. 94.80 mM

Smiles

Oc1c (C (C) (C) C) cc (/C=C (\C#N) /C (=S) N) cc1C (C) (C) C

Molecular Formula

C18H24N2OS

Molecular Weight

316.46

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Propenethioamide, 3- (3,5-bis (1,1-dimethylethyl) -4-hydroxyphenyl) -2-cyano-, (E) -

Available Sizes

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