GSK2801
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI.
Product Specifications
CAS Number
1619994-68-1
Product Name Alternative
GSK2801 | GSK-2801 | GSK 2801
Purity
>98% (HPLC)
Solubility
DMSO : 50 mg/mL. 134.61 mM; H2O : < 0.1 mg/mL
Smiles
CCCOc1cc2c (cc (n2cc1) C (=O) C) c1ccccc1S (=O) (=O) C
Molecular Formula
C20H21NO4S
Molecular Weight
371.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (1- (2- (methylsulfonyl) phenyl) -7-propoxyindolizin-3-yl) ethanone
Available Sizes
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