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LJI308

LJI308 is a RSK inhibitor. LJI308 overcomes chemoresistance by eliminating cancer stem cells. LJI308 targets the CSC population and repress TNBC growth and dissemination. LJI308 specifically targeted transformed cells as it had little effect on the non-tumorigenic parental HMECs. Targeting RSK using specific and potent inhibitors, such as LJI308, delivers the promise of inhibiting the growth of TNBC.

Product Specifications

CAS Number

1627709-94-7

Product Name Alternative

LJI308 | LJI-308 | LJI 308 | NVP-LJI308 | NVP-LJI-308

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 32 mg/mL 86.87 mM

Smiles

Oc1c (F) cc (cc1F) -c1cnccc1-c1ccc (cc1) N1CCOCC1

Molecular Formula

C21H18F2N2O2

Molecular Weight

368.38

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2,6-Difluoro-4-[4-[4- (4-morpholinyl) phenyl]-3-pyridinyl]-phenol

Available Sizes

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