FTI 277 hydrochloride
FTI 277 hydrochloride is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM) ; this selectivity is about 100-fold than the closely related GGTase I.
Product Specifications
CAS Number
180977-34-8
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 4.9 mg/mL; 10.12 mM
Smiles
COC (=O) [C@H] (CCSC) NC (=O) c1c (cc (cc1) NC[C@H] (CS) N) c1ccccc1.Cl
Molecular Formula
C22H30ClN3O3S2
Molecular Weight
484.07
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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