Lomitapide
Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.
Product Specifications
CAS Number
182431-12-5
Product Name Alternative
AEGR-733 | BMS-201038
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 35 mg/mL; 50.45 mM
Smiles
C1cccc2c1C (c1c2cccc1) (CCCCN1CCC (CC1) NC (=O) c1c (cccc1) c1ccc (cc1) C (F) (F) F) C (=O) NCC (F) (F) F
Molecular Formula
C39H37F6N3O2
Molecular Weight
692.71
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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