SC-560
SC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.
Product Specifications
CAS Number
188817-13-2
Product Name Alternative
SC-560 | SC 560 | SC560
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL
Smiles
COc1ccc (cc1) n1c (cc (n1) C (F) (F) F) c1ccc (cc1) Cl
Molecular Formula
C17H12ClF3N2O
Molecular Weight
352.74
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5- (4-chlorophenyl) -1- (4-methoxyphenyl) -3- (trifluoromethyl) -1H-pyrazole
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