PD-166866
PD166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD166866 has clear antiproliferative effects.
Product Specifications
CAS Number
192705-79-6
Product Name Alternative
PD166866 | PD166866 | PD 166866
Purity
>98% (HPLC)
Solubility
DMSO : 10.33 mg/mL. 26.06 mM
Smiles
COc1cc (OC) cc (c1) -c1cc2cnc (N) nc2nc1NC (=O) NC (C) (C) C
Molecular Formula
C20H24N6O3
Molecular Weight
396.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (2-amino-6- (3,5-dimethoxyphenyl) pyrido[2,3-d]pyrimidin-7-yl) -3- (tert-butyl) urea.
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