EAI045
EAI045 ia a potent and selective EGFR inhbitor. EAI045 targets selected drug-resistant EGFR mutants but spares the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays.
Product Specifications
CAS Number
1942114-09-1
Product Name Alternative
EAI045 | EAI-045 | EAI 045
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 28 mg/mL; 73.03 mM
Smiles
C1ccc2c (c1) CN (C2=O) C (C (=O) Nc1sccn1) c1cc (ccc1O) F
Molecular Formula
C19H14FN3O3S
Molecular Weight
383.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (5-fluoro-2-hydroxyphenyl) -2- (3-oxo-1H-isoindol-2-yl) -N- (1,3-thiazol-2-yl) acetamide
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